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Stars stand for the overview status, or the level of evaluate supporting the submitted (SCV) file. This value is calculated by NCBI based upon information with the submitter.
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ClinVar incorporates an entry for this variant (Variation ID: 574387). Variants that disrupt the consensus splice web-site are a relatively common reason behind aberrant splicing (PMID: 17576681, 9536098). Algorithms produced to forecast the result of sequence changes on RNA splicing advise that this variant could create or strengthen a splice web-site. In summary, the obtainable proof is presently inadequate to determine the position of this variant in ailment. Therefore, it's been categorized for a Variant of Unsure Significance. Okay
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The impact in the variant on RNA or protein perform, depending on experimental proof from submitters.
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